lec38 - Lecture 38/39 Developmental genetics I....

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Picture 167 Picture 16 Picture 182 Lecture 38/39 – Developmental genetics I. Developmental genetics A. requirements for development 1. cell proliferation 2. mechanisms for generating cell differences a. specification – cell fates become restricted - early      pluripotent - later       more restricted in developmental potential b. two general mechanisms i. asymmetric segregation of  ii. cell-cell signaling determinants B.  Drosophila  early development – A-P axis patterning 1
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Picture 168 1. Why  Drosophila ? 2. fly development in overview: 2
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Picture 169 Picture 170 3. anterior-posterior body axis – concentration gradient of key transcription factors that  act as morphogens - morphogen –  3
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Picture 171 Picture 172 4. proteins expressed in gradients regulate  expression of next level of patterning, the gap genes - gap genes divide embryo into distinct domains
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This note was uploaded on 07/01/2011 for the course L 311 taught by Professor Forrester during the Fall '10 term at Indiana State University .

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lec38 - Lecture 38/39 Developmental genetics I....

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