L567 Lecture 2 - L567 Lecture 2 L567 Lecture 2. A brief...

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L567 Lecture 2 L567 Lecture 2. A brief history of population genetics (from Provine’s book), and basic theoretical population genetics. Intuitive understanding of e = mc 2 , or R = h 2 S? Intuitive understanding of R = h 2 S requires unpacking h 2 , which requires an understanding of variance, covariance of regression. That is where we are going. Also, in addition to Peters’ attack on Natural Selection, Karl Popper (famous philosopher) also hammered the theory: Darwinism is not a testable scientific theory, but a metaphysical research program. But he later changed his mind: I have changed my mind about the testability and logical status of the theory; and I am glad to have an opportunity to make a recantation.” Popper realized that the theory was testable. 1
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L567 Lecture 2 Darwin’s views on variation prior to 1856 2 types of variation, both heritable Sports: large, discrete effect Individual differences: small continuous effects Darwin’s view in 1856: The Origin of Species a) Sports are too rare b) Darwin concludes that selection operates on “individual differences.” Variation in these differences is generated every generation. Change is gradual Reaction to The Origin of Species --Evolution as such accepted --Natural selection rejected. Darwin’s view in 1868. The provisional theory of pangenesis a) gemmules circulate through the body. b) gemmules change and the environment affects the body c) gemmules collect and multiply in reproductive organs, and pass on acquired characteristics d) gemmules have small, additive effects (due to blending). 2
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L567 Lecture 2 The problem with blending inheritance a) variation needed for natural selection is lost in the blender.
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This note was uploaded on 07/01/2011 for the course L 567 taught by Professor Curtis during the Fall '10 term at Indiana State University .

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L567 Lecture 2 - L567 Lecture 2 L567 Lecture 2. A brief...

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