9-15 11 AM Pathogenesis & genetics

9-15 11 AM Pathogenesis & genetics - Virus...

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Virus pathogenesis and genetics
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Viral pathogenesis Cycle of infection Entry Primary site replication Spread within the host Shedding Transmission Effects on cells Effects on organism
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Definitions Tropism what cells within the host does the virus infect? influenced by cellular receptors, intracellular Prodrome early disease symptoms which are mild or non- specific Fomite an inanimate object or substance that is capable of transmitting infectious organisms from one individual to another
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Cycle of infection Secondary sites Spread Entry Shedding Shedding Local Lymphatic Neuronal Blood (viremia) Primary site
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Entry Mucous membranes or skin Respiratory Oral Sexual Ocular Percutaneous needles, wounds, bites
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Shedding, transmission Routes Respiratory Gastrointestinal (oral-fecal) Urogenital Skin Mechanisms Indirect contact Aerosols Fomites Direct contact Lesions Saliva Sex Animal or insect bites Maternal-neonatal
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This note was uploaded on 07/02/2011 for the course MMC 6500 taught by Professor Gulig during the Spring '11 term at University of Florida.

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9-15 11 AM Pathogenesis & genetics - Virus...

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