9-21_11_AM_Enterovirus

9-21_11_AM_Enterovirus - Stranded RNA Viruses I Polio The...

Info iconThis preview shows pages 1–7. Sign up to view the full content.

View Full Document Right Arrow Icon
(+) Stranded RNA Viruses I Polio The Common Cold Norwalk Virus
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Totally Paralyzed Poliomyelitis Patients in Mechanical Respirators Last US epidemic before universal immunization (1955).
Background image of page 2
Picornaviridae   family 1.  Enterovirus a) Polioviruses  types 1, 2 and 3 b) Coxsackieviruses A1-A24 (no A23), B1-B6 c) Echoviruses 1–34 (no 10 or 28) d) Enteroviruses 68 -71 2.  Rhinovirus a) Rhinoviruses 1 -100+ 3.  Hepatovirus a) Hepatitis A virus 4.  Cardiovirus Caliciviridae   family 1. Norwalk virus 2. Hepatitis E virus
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Biologic properties Heat and detergent stable Acid stability (ability to survive gastric acids following ingestion) a. Enterovirus, Hepatovirus , and Calicivirus are acid-stable (pH >3) b. Rhinovirus is acid-labile (pH <5)
Background image of page 4
Virion structure 1. Picornaviridae : non-enveloped icosahedral capsid, 30 nm in diameter, 60 protomers 2. Caliciviridae : nonenveloped icosahedral capsid, 30 – 38 nm, 90 capsomers; named for the 32 characteristic cup-shaped depressions on the virion surface
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Genome structure 1. Linear, plus sense ssRNA, 7 – 8 kb 2. Protein primer at 5’ end, polyadenylated at 3’ end 3. Genome RNA is infectious
Background image of page 6
Image of page 7
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 07/02/2011 for the course MMC 6500 taught by Professor Gulig during the Spring '11 term at University of Florida.

Page1 / 27

9-21_11_AM_Enterovirus - Stranded RNA Viruses I Polio The...

This preview shows document pages 1 - 7. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online