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Unformatted text preview: d[ES] = k for [E][S] (Appearance of T.S.) dt Now set appearance of [ES] equal to the disappearance of [ES] (Steady-state assumption) d[ES] =-d[ES] ; k for [E][S] = k B T/h[E][S] e- G /RT (Cancel [E][S] terms) dt dt k for = k B T/h e- G /RT (Kinetic k for related to thermodynamic G ) So, from the equation derived if G is large, then the k for will be low and the overall rate is slow. And if the G is small, then the k for will be high and the overall rate is fast. There is an inverse relationship between G and k for due to the e- G term....
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This note was uploaded on 07/10/2011 for the course BCH 4033 taught by Professor Stern during the Summer '11 term at UNF.
- Summer '11