BIO 207 (Human Physiology) Exam 1 Study Guide

BIO 207 (Human Physiology) Exam 1 Study Guide - CHAPTER 1...

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                 CHAPTER 1 OUTLINE u Introduction to Physiology u Scientific Method u Homeostasis u The Primary Tissues muscle tissue nervous tissue epithelial tissue connective tissue 1-2
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Human Physiology Physiology : study of how body works to maintain life Pathophysiology : how physiological processes are altered in disease or injury 1-3
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Scientific Method 1. Form a testable hypothesis about observations 2. Conduct and analyze experiments to test hypothesis 1-5
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Testing of Hypotheses ² Involves: Ø Experimental and control groups Ø Quantitative measurements performed blindly Ø Analysis of data using statistics 1-6
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² When a new drug is suggested by experiments: Its effectiveness and toxicity is tested first in tissue culture, rats, mice ² 1-
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Using Scientific Method to  Develop New Drugs If effective and safe, clinical trials performed ² Phase I Trials : Toxicity and metabolism tested in healthy human volunteers ² Phase II Trials : Effectiveness and toxicity tested in target population ² Phase III Trials : Widespread test of drug in diverse population ² Phase IV Trials : Drug is tested for other potential uses 1-8
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Homeostasis Is maintenance of a state of dynamic constancy In which conditions are stabilized above and below a physiological set point Ø By negative feedback loops 1-10
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Negative Feedback Loops § Sensor : Detects deviation from set point § Integrating center : Determines response § Effector : Produces response 1-11
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Homeostasis  continued Regulatory mechanisms: Intrinsic control is built into organ being regulated 1-12
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Homeostasis  continued Regulatory mechanisms: Extrinsic control comes from outside of organ E.g. body temperature is controlled by antagonistic effects of sweating and shivering 1-13
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This note was uploaded on 06/27/2011 for the course BIO 207 taught by Professor Fishwild during the Summer '11 term at Oakland University.

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BIO 207 (Human Physiology) Exam 1 Study Guide - CHAPTER 1...

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