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Review problems Unit III

Review problems Unit III - Review problems Chapter 27...

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Review problems Review problems Chapter 27 Chapter 27 Dr.Sanghamitra Mohanty
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    Q 1.  Calculate the frequencies of the AA, Aa, and aa genotypes after one  generation if the initial population consists of AA 0.2, Aa 0.6 and aa 0.2 and  the population is in Hardy-Weinberg equilibrium. A = p, a = q, Aa = 2pq p = 0.2 + (0.5) (0.6) = 0.5 q = 1- 0.5 = 0.5 Frequency of AA = p 2  = (0.5) 2  = 0.25 = 25% Frequency of aa = q 2  = (0.5) 2  = 0.25 = 25% Frequency of Aa = 2pq =2 (0.5) (0.5) = 0.5 = 50%
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    Q 2. Determine whether the following set of data represent a population that is in Hardy- Weinberg equilibrium. CCR5 genotypes: 1/1 =60%, 1/32 = 35% and 32/32 = 5% ( observed  genotype frequencies) Suppose the population consists of 100 individuals, then 1/1 =60/100 = 0.6, 1/32 =35/100 =  0.35 and 32/32 = 0.05 Allelic frequencies will be, 1 = 0.6 + (0.5) (0.35) = 0.775 (p) 32 = 0.05 + (0.5) (0.35) = 0.225 (q) Expected
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