Unformatted text preview: Name: 4* A Student Number: _ _ 7, -_.Ā»-ļ¬: FUNDAMENTALS OF IMMUNOLOGY Instructions: Use only PEN to complete the test (pencil WILL NOT be remarked). ā Please read every question carefully and completely. Section A ā Fill-ināthe-blank. (22 marks) Fill in the blank with the most correct word or phrase. Each blank is worth 1 mark. 1. Besides the immune cells and antibodies weāve learned about, the body has many āinnateā,
physical and chemical defenses, sometimes speciļ¬c to compartments (6. g. mucosal
surfaces) that repel the vast majority of potential pathogens. (3 marks) List three of these physical or chemical defenses: Russ; M lsālromoeh low Eā 1 Tight Somehow :h__ Ā¢Qiimligm E L so: me. mmĀ»; cuisines)
2. The study of innate immunity has been revitalized due to better appreciation for the
importance of non-speciļ¬c antigen recognition in shaping the overall innnune response.
(6 marks) Toll-like receptors (TLR) are one subfamily of a larger family of Pattern RE%ā āā105 Ā«ace 5 receptors that bind macromolecules with conserved pathogen-
associated molecularyems, for example LPS Ll pnglgsmhmae) , and
cls KN Pt ; TLRs are expressed by most cells of the igngāie 1/ immune system, for example m achets . a? mint: Tact Ā£1 not 731 9mm Page 1 of 7 ...
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- Spring '11