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101_11AI-neuro6-ANS_ENS_SNS

101_11AI-neuro6-ANS_ENS_SNS - topic set#6 now know some...

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convergence & integration divergence transmitter release topic set #6: now know some mechanisms for signal flow through individual neurons signal transmission spike generation spike propagation post-synaptic potentials short, medium & long distance effects Fig 4-19 npb101-w2011-ishida questions: where do the inputs come from? what stimulates these paths? where do the outputs go? what tissues do these paths control? now, look at specific circuits & functions npb101-w2011-ishida
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goal recruit efferents, afferents, circuits for various involuntary responses & voluntary acts 1) move 1) move limbs by coordinated contraction & relaxation of skeletal muscle 2) maintain posture 2) maintain limb position 3) ingest water 3) swallow water 4) digest food 4a) chew & swallow food 4b) adjust glandular secretions (e.g., saliva) 4c) adjust contractions of smooth muscle to move partially digested food through GI tract 5) circulate blood 5) adjust cardiac output 6) breathe; eliminate CO 2 6) inflate/deflate lungs 7) adjust passage of waste 7) tighten/relax sphincters in gastrointestinal & renal systems 8) adjust light entering eye 8) adjust iris (smooth muscle) 9) transduce, integrate, process, route signals 9) receptors (stretch, smell, taste, osmolarity, pH, blood pressure, light , touch, temperature, pain ); spinal circuits; brainstem centers; cranial nerves; cortico- spinal projections npb101-w2011-ishida goal efferents, afferents, circuits 4 nervous systems based on location & what they control 1) move 1) move limbs by coordinated contraction & relaxation of skeletal muscle autonomic enteric somatic motor central 2) maintain posture 2) maintain limb position 3) ingest water 3) swallow water 4) digest food 4a) chew & swallow food 4b) adjust glandular secretions (e.g., saliva) 4c) adjust contractions of smooth muscle to move partially digested food through GI tract 5) circulate blood 5) adjust cardiac output 6) breathe; eliminate CO 2 6) inflate/deflate lungs 7) adjust passage of waste 7) tighten/relax sphincters in gastrointestinal & renal systems 8) adjust light entering eye 8) adjust iris (smooth muscle) 9) transduce, integrate, process, route signals 9) receptors (stretch, smell, taste, osmolarity, pH, blood pressure, light, touch, temperature, pain); spinal circuits; brainstem centers; cranial nerves; cortico-spinal projections npb101-w2011-ishida
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1 “nervous system” autonomic enteric location afferents in targets & related tissues efferents originating in spinal cord some cranial nerves within digestive tract brainstem neurons outside digestive tract function control of cardiac muscle smooth muscle exocrine glands endocrine glands involuntary control of smooth muscle exocrine glands endocrine glands Fig 7-3 note: this show efferents only npb101-w2011-ishida enteric location within digestive tract thus, sensory & command – not afferent /efferent brainstem neurons outside digestive tract function involuntary control of smooth muscle exocrine glands endocrine glands 2 nd “nervous system” see Figs 5-20 & 16-2 Bear’96 Fig 16-10 npb101-w2011-ishida
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enteric location within digestive tract
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