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1 The Endocrine System Part II: Hypothalamus and Pituitary Lecture 40 and 41 Recommended reading: Sherwood 6 th edition Chapter 18 pp. 662-676 Sherwood 7 th edition Chapter 18 pp. 670-685 Anatomy of the pituitary gland Posterior pituitary gland/relationship to the hypothalamus Control of anterior pituitary hormone secretion by the hypothalamus Hormones of the anterior pituitary Discovery of hytpothalamic releasing or inhibiting hormones Control of hormone secretion by negative feedback loops Growth hormone Control of secretion Effects on metabolism Effects on bone growth Growth hormone excess/deficiency Topics to be covered in these lectures
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2 Some hormones are secreted directly in response to changes in plasma constituents: Insulin and Glucagon: changes in blood glucose levels Aldosterone: changes in blood pressure, osmolarity activate the renin/angiotensin system Parathyroid Hormone (parathyroid glands) and Calcitonin from (C cells in the thyroid gland) are sensitive to Ca2+ levels and work to maintain Ca2+ homeostasis (in concert with Vitamin D) Fig. 5-15, p. 155 However, several major endocrine control systems are under the control of the hypothalamus and nearby pituitary gland Anatomy of the Pituitary Gland Fig. 18-4, p. 670 Neural portion Glandular portion
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This note was uploaded on 07/09/2011 for the course NPB 101 taught by Professor Fuller,charles/goldberg,jack during the Winter '08 term at UC Davis.

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