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Unformatted text preview: LOWER RESPIRATORY SYSTEM D ISEASE AGENT V IRULENC E FACTORS SYMT OMS prevenT ion treatme nt Lab id test OTHER (bacterial) PERTUSS IS (whooping cough) Bordetella pertussis *gram negative coccobacillus Virule nt strain s contai n capsul e **Bacteria attach to specifically ciliated cells in trachea, impeding their ciliary action and destroying cells (prevents escalator system from moving mucous) Trache al cytoto xin: in cell wall, damag es ciliate d cells Pertus sis toxin: increa sed respir atory secreti ons STAGE 1: (catarrhal stage)-common cold symptoms STAGE 2: (paroxysmal stage)-violent coughing sieges to cough up mucus-can break ribs in children (whooping sound) STAGE 3: (covalence stage)-can last for months DT aP vaccine ( a cellular p ertussis cell fragments) Antibiotics: Erythromyci n or other macrolides *not as effective after paroxysmal stage begins but can reduce transmittion Diagnosis primarily based on clinical symptoms Throat swab(inserted through nose) while patient coughs can be cultured or PCR diagnostic tested for pathogen *introduction of PCR diagnostic test can lead to greater amount of reported cases (psuedoepedemic) (bacterial) TUBERC ULOSIS M. Bovis: pathogen of mainly cattle; causes bovine tuberculosis transmitted to humans by milk or food (<1% U.S cases) M. Avium intracellular Primarily affects people with late stage HIV infection Myobacteriu m tuberculosis *acid fast rods that grow slowly and transmitted from human to human-large amounts of lipids in cell wall account for bacteriums acid-fast characteristics (can not be decolorized with acid alcohol) and...
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This note was uploaded on 07/12/2011 for the course NURSING 000 taught by Professor Clark during the Spring '11 term at Alabama.
- Spring '11