WHOconsensus - WHO/CDS/CSR/GAR/2003.11 1 Consensus document...

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WHO/CDS/CSR/GAR/2003.11 1 Consensus document on the epidemiology of severe acute respiratory syndrome (SARS) D EPARTMENT O F C OMMUNICABLE D ISEASE S URVEILLANCE A ND R ESPONSE
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WHO/CDS/CSR/GAR/2003.11 Consensus document on the epidemiology of severe acute respiratory syndrome (SARS) D EPARTMENT O F C OMMUNICABLE D ISEASE S URVEILLANCE A ND R ESPONSE
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Acknowledgement This document has been produced by the Severe Acute Respiratory Syndrome (SARS) Epidemiology Working Group and the participants at the Global Meeting on the Epidemiology of SARS, 16-17 May 2003. © World Health Organization 2003 All rights reserved. The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters. The World Health Organization does not warrant that the information contained in this publication is complete and correct and shall not be liable for any damages incurred as a result of its use.
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Consensus Document on the Epidemiology of SARS WHO/CDS/CSR/GAR/2003.11 1 Table of Contents I. Introduction . ..................................................................................................................... 2 II. Recommendations from the global meeting on the epidemiology of SARS . ...................... 3 1. Incubation period. ............................................................................................................ 3 2. Infectious period . ............................................................................................................. 3 3. Case-fatality ratios. .......................................................................................................... 4 4. Routes of transmission, exposure dose and risk factors for transmission. ....................... 4 5. The presence and significance of subclinical infection . .................................................... 5 6. Reproduction number in different transmission settings and under different control strategies . ................................................................................................................. 5 7. Animal and environmental reservoirs . ............................................................................. 6 8. Cross-cutting issues . ...................................................................................................... 6 III. Key epidemiological distributions. ................................................................................... 7 1. Incubation period. ............................................................................................................ 7 2. Infectious period . ............................................................................................................. 8 3. Case-fatality ratios. ........................................................................................................ 10 IV. Routes of transmission and effective prevention of transmission . ............................... 12 1. Routes of transmission. ................................................................................................. 12 2. Risk factors for transmission. ........................................................................................ 13 2.1 The global epidemiology of SARS . ................................................................................. 13 2.2 Risk factors for SARS. ................................................................................................... 14 2.3 Special populations requiring investigation. ................................................................. 14 2.4 Airline transmission . .................................................................................................... 17 3. The SARS experience by geographical area . .................................................................. 18 V. The presence and significance of subclinical infection . ............................................... 25 VI. Reproduction number in different transmission settings and under different control conditions. ...................................................................................................................... 26 VII. Animal and environmental reservoirs . ........................................................................ 27 1. Animal reservoirs . ...........................................................................................................
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WHOconsensus - WHO/CDS/CSR/GAR/2003.11 1 Consensus document...

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