Unformatted text preview: Use electrophoresis to see if the unhybridized T cell cDNA have gene rearrangement (f so, prooves there’s TCR) 2. Structure of TCR TCR: an alpha-beta heterodimer 3. TCR signal transduction after T cell activation changes in gene expression (for differentiation into effector + memory cells – all with same TCR) a. Early signaling pathway b. Downstream pathways...
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This note was uploaded on 04/04/2008 for the course MCB 150 taught by Professor Coscey during the Spring '08 term at Berkeley.
- Spring '08