ANS3319CReprod_CyclicityLuteal_Phase_KEY_Final_Topic10 -...

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ANS 3319C Reproductive Physiology and Endocrinology Luteal Phase 103 Reproductive Cyclicity: Luteal Phase 1) Review of luteal phase Metestrus, Diestrus (Luteolysis) See Figures 9-3 to 9-5 2) Corpora lutea or corpus luteum formation (luteinization) Origin: theca interna & granulosa cells of ovulated follicle Anatomy of ovulation & luteinization (Fig 9-2) Preovulatory follicle: Breakdown basement membrane Mixing theca interna/granulosa cells Ovulation: rupture of tunica albuginea Corpus hemorrhagicum formation: Theca/granulosa mix Follicle walls collapse, fold on it self Basement membrane connective tissue Corpus luteum formation: Granulosa cells large luteal cells (LLC) Theca interna small luteal cells (SLC) vascularization
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ANS 3319C Reproductive Physiology and Endocrinology Luteal Phase 104 Functional capacity of CL: ability to produce progesterone Driven by LH Progesterone as CL volume (Figs 9-3 to 9-6) SLC # by hyperplasia & LLC size by hypertrophy Vascularization of CL Amount varies, due to angiogenic factors in follicular fluid Insufficient luteal function ( progesterone) Associated with inability of uterus to support pregnancy Large Luteal Cells (LLC) Granulosa cell origin Ruminants: secretory granules CL of estrous cycle: oxytocin CL pregnancy: relaxin Hypertrophic growth > 80% progesterone produced High basal progesterone
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ANS3319CReprod_CyclicityLuteal_Phase_KEY_Final_Topic10 -...

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