EPI Exam 2 Study Guide - Case-control studies major sources...

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Unit 5 – Cohort Studies Know the following: Prospective &Retrospective study designs Design features: exposure, outcome measurement Measures of association for cohort studies (risk and rate ratios) Healthy worker effect Standardized and proportionate mortality ratios Strengths and weaknesses of cohort designs Read the following: Oleckno, Ch. 4 (p. 47-49), Ch. 6 (p.106 to bottom of p. 110), Ch. 12 Unit 6 – Validity of Associations Know the following: Internal validity: chance Statistical power p-values and confidence intervals Statistical vs. biologic significance Read the following: Oleckno, Ch. 8 (p. 137-139, 151-154), Ch. 11 (p. 212-213, statistical/biologic significance) Unit 7 – Bias
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Know the following: Selection and observation Cohort studies: major sources of bias
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Unformatted text preview: Case-control studies: major sources of bias Misclassification: differential vs. non-differential Internal vs. external validity Read the following: Oleckno, Ch. 8 (p. 140-147); Ch. 11 (p. 208-212), Ch. 12 (p. 232 paragraphs 2 & 3) Unit 8 – Confounding & Effect Modification Know the following: Basic concepts and control: restriction, matching, stratification, multivariate analysis, randomization Direct and indirect standardization Stratified analysis and the Mantel-Haenszel adjusted odds ratio McNemar s test ‟ Effect-modification: definition using stratified analysis Read the following: Oleckno, Ch. 6 (review p. 91-100; read p. 101-105); Ch. 8 (p. 148-158); Ch. 11 (p. 213-228); Ch. 13 (p. 257-259)...
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