lec 4 Tetrad analysis additional slides

lec 4 Tetrad analysis additional slides - Case 1: unlinked...

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Linkage Between the ABO and Nail-Patella Loci • 4/13 offspring (31%) in this pedigree are recombinant. • Combining data from many pedigrees, the genetic distance between the ABO and NPS1 loci is 10 cM.
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Yeast tetrads demonstrate crossing over is reciprocal and occurs between chromatids
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Linkage mapping in yeast by scoring meiotic tetrads
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Unformatted text preview: Case 1: unlinked genes PD = NPD Case 2: linked genes PD > NPD Recombination frequency* = [(1/2)T + NPD] / total asci PD T PD NPD T * Underestimates distance by failing to count double cross-overs (see text page 148) counted as one crossover not counted counted counted Centromere mapping in Neurospora...
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This note was uploaded on 07/17/2011 for the course BIO 151 taught by Professor Grinblat during the Summer '08 term at Wisconsin.

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lec 4 Tetrad analysis additional slides - Case 1: unlinked...

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