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51822_cramster8 - Genetics All Your Hopes and All Your...

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Genetics All Your Hopes and All Your Fears
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Genetics Classical Genetics Mendelian genetics Fundamental principles underlying transmission of genetic traits Forward genetics Identify or generate phenotypically mutant organisms Determine mode of inheritance and interactions with other mutants Identify mutated gene(s) Correlate observed phenotype with biochemical mechanisms
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Genetics Molecular Genetics Based on classical approaches Refers to techniques applied to study genetic questions Most modern genetic studies are molecular Reverse genetics Genes identified 1st Gene mutated by molecular biology techniques Mutant gene inserted into genome of organism and resulting phenotype studied
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History of Genetics Domestication of plants & animals suggests prehistoric peoples recognized concept of heredity Traits passed from parent to offspring Selection of desirable traits – artificial selection
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History of genetics Ancient Greeks Mostly bunk Renaissance 1600-1800 Theories of epigenesis vs preformation 1800s – turn to a more reductionist approach Dalton's Atomic theory Schwann's cell theory
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History of Genetics Mid 19 th century (1850) Darwin & Wallace Theories of evolution Lamarck Theories on acquisition of heritable traits Mendel Theories on transmission of traits
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This note was uploaded on 07/20/2011 for the course BIO 101 taught by Professor Krm during the Summer '11 term at LSU.

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51822_cramster8 - Genetics All Your Hopes and All Your...

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