Ch13 HardyWeinbergProblems

Ch13 HardyWeinbergProblems - Molecular Biology Chapter 13...

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Molecular Biology Chapter 13: Evolution Hardy-Weinberg Practice Problems When Allele Frequencies Are Given 1. Given a population in Hardy-Weinberg equilibrium with allele frequencies A = 0.9 and a = 0.1, determine the frequencies of the three genotypes AA, Aa and aa. 2. In a population that is in Hardy-Weinberg equilibrium, the frequency of the ±z² allele is 0.6. What percentage of the population is heterozygous at this locus? Recessive Traits 3. Allele W for white wool is dominant over allele w for black wool. In a sample of 900 sheep, 891 are white and 9 are black. Estimate the allelic frequencies in this sample. 4. In corn, yellow kernel color is governed by a dominant allele; white, by a recessive allele. A random sample of 1,000 kernels from a population that is in equilibrium reveals that 910 are yellow and 90 are white. What are the frequencies of the yellow and white alleles in this population? What is the percentage of heterozygotes in this population? 5. The compound phenylthiocarbamide (PTC) tastes very bitter to most persons. The inability to taste PTC is controlled by a single recessive allele. In the American white population, about 70% can taste PTC while 30% cannot (are non-tasters). Estimate the frequency of the Taster (T) and non-taster (t) alleles in this population as well as the frequencies of the diploid genotypes. 6. 1 in 1,700 US Caucasian newborns have cystic fibrosis. C for normal is dominant over c for cystic fibrosis. a) What percentage of the above population has cystic fibrosis (cc)?
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b) Calculate the frequencies of the C and c alleles. c)
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This note was uploaded on 07/21/2011 for the course BIO 1B taught by Professor Carlson,mischel,power during the Spring '07 term at Berkeley.

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Ch13 HardyWeinbergProblems - Molecular Biology Chapter 13...

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