4124 GI tract powerpoint for exam 4

4124 GI tract powerpoint for exam 4 - Click to edit Master...

Info iconThis preview shows pages 1–11. Sign up to view the full content.

View Full Document Right Arrow Icon
Click to edit Master subtitle style 7/22/11
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Click to edit Master subtitle style 7/22/11 Gastrointestinal Tract infections
Background image of page 2
7/22/11 Diarrhea Increase in fluid and electrolyte loss into the lumen of the gut Gastroenteritis Common causes Campylobacter jejuni E.coli Salmonella spp. Viruses: Rota Rarer causes Bacillus cereus Clostridium perfringens Food poisoning Disease caused by ingestion of food contaminated with a toxin
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
7/22/11 Pathogenesis Preformed toxins Present with short incubation with vomiting C. botulinum and Staph. aureus Toxins produced in the gut Longer incubation period with marked vomiting V. cholerae and Enterotoxigenic E. coli Tissue invasion Entoamoeba histolytica, Salmonella spp ., Enteroinvasive E. coli Parasitism Protozoa and worms
Background image of page 4
7/22/11 Enteric Pathogens Enteric bacteria – rod-shaped Gram-negative bacteria; most occur normally or pathogenically in intestines of humans and other animals escherichia klebsiella salmonella shigella
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
7/22/11 Enterobacteriaciae G- rods which ferment glucose; oxidase negative Facultative anaerobes Serotypes O antigens- LPS H antigens- flagellar K antigens- capsular or fimbrae
Background image of page 6
7/22/11 EPEC Developing countries Destroy gut microvilli No toxins Use bundle forming pili and intimin (adhesin) to disrupt epithelial cell Enteropathogenic E. coli
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
7/22/11 ETEC The major cause of travelers diarrhea and diarrheal disease in children in developing countries Transmitted by food or water contaminated with human or animal feces Self limiting Two toxins which stimulate the lining of the intestines to secrete excessive fluid (heat stable- ST; heat labile- LT) Watery diarrhea, abdominal cramping, low-grade fever, and nausea Illness occurs 1-3 days after exposure and last 3-4 days on average
Background image of page 8
7/22/11 Replace liquids Anti-motility agents may reduce number of bowel movement but can prolong disease and should be avoided in cases of bloody diarrhea and fever. Kaolin-pectin compounds or lactobacillus do not slow or relieve symptoms Avoid milk products, because temporary lactose intolerance is common after
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Enterhaemorrhagic E. coli EHEC or VTEC Serotype 0157:H7 Produce verotoxin (shiga toxin) which binds to gut mucosal and kidney leading to damage and hemorrhage Symptoms Acute bloody diarrhea with severe abdominal cramps with little or no fever which last approximately 1 week May cause hemorrhagic colitis (HC) and hemolytic-uremic syndrome (HUS) associated with hemolytic anemia, thrombocytopenia and acute renal failure in 5% of infections and the principal cause of acute renal failure in children under 5. Transmission is from undercooked ground beef, raw milk,
Background image of page 10
Image of page 11
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 07/22/2011 for the course BIOL 4124 taught by Professor Hale-donze,h during the Spring '08 term at LSU.

Page1 / 44

4124 GI tract powerpoint for exam 4 - Click to edit Master...

This preview shows document pages 1 - 11. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online