Enzyme Nomenclature

Enzyme Nomenclature - water to displace...

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7/24/11 Name What it does Synthase Condensation reactions that do not require an NTP Synthetase Condensation reactions that DO require an NTP to work Ligase Condensation reactions that require an NTP or another energy source to work, and join two atoms together Lyase Cleavage reactions that involve electronic rearrangements Kinase Transfer of a phosphate from an NTP to another molecule (phosphorylation) Phosphoryla se A phosphate is used to displace another group, and becomes attached at the point where that bond is broken (phosphorolysis) Phosphatase Removes a phosphoryl group from another molecule, using
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Unformatted text preview: water to displace it (dephosphorylation) Dehydrogen ase Oxidizes a substrate by transferring a H- to an acceptor like NAD(P)+ or FAD Isomerase Interconverts one isomer into another isomer Mutase Transfers a functional group (eg. a phosphate) from one place to another within a single molecule Transferase Transfers a function group from one molecule to another Epimerase Switches the stereochemistry of an asymmetric carbon in a molecule that has another asymmetric carbon in it Be aware that many enzymes are named (for historical reasons) for their REVERSE reactions!...
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