Paper35-Histological-biological-effects-granulation-tissue-loosened hip-development-osteolysis-J-Ort

Paper35-Histological-biological-effects-granulation-tissue-loosened hip-development-osteolysis-J-Ort

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Unformatted text preview: 21) (22) (23) (24) (25) (26) (27) (28) (29) (30) (31) (32) (33) (34) (35) (36) (37) (38) (39) (40) mRNA increased, while that of collagen I mRNA was unchanged (Fig. 10). Discussion In this study, we analyzed periprosthetic tissues from patients with aseptic loosening and demonstrated the presence of macrophage/histiocytes, foreign body giant cells, and polyethylene particles in various grades. These findings were consistent with previous histological studies on osteolysis in joint replacement5,6,18 484 S. Ito et al.: Granulation tissue in osteolysis Fig. 5. Relationship of the histological grade of particles or giant cells in the granulation tissue around the socket between prostheses with and without cement. Bars represent the mean SEM b a c and experimental animal models.13,16 Unexpectedly, polyethylene particles were not always present in our samples, similar to the results shown by Kim et al.14 that the percentage of specimens with polyethylene particles graded as moderate or severe was 52%–63%. This may be explained as follows: osteolysis...
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This note was uploaded on 07/25/2011 for the course EMA 6580 taught by Professor Staff during the Spring '08 term at University of Florida.

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