Paper35-Histological-biological-effects-granulation-tissue-loosened hip-development-osteolysis-J-Ort

2 since most cases involved in this study showed

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Unformatted text preview: was caused by other mechanisms such as mechanical stress,17 or there were submicron polyethylene particles that were too small to be detected by light microscopy.2 Since most cases involved in this study showed mechanical instability, Fig. 6a–c. A case of massive osteolysis (case 19). A 56-year-old man had received an Omnifit bipolar femoral head replacement 13 years earlier. a Roentgenogram of the failed femoral component before the revision; b photomicrograph of granulation tissue around the loosened prosthesis (hematoxylin and eosin, 100); c polarized light photomicrograph (hematoxylin and eosin, 100) both factors were related to osteolysis. It is known that particles smaller than 8–10 µm are phagocytosed by histiocytes, while bigger particles induce giant cell reaction and are associated with such cells.23 In support of this, the number of giant cells significantly correlated with polyethylene particles. These results may indicate larger particles, but not submicron particle...
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