lecture 38 - Lecture 38 Final Exam 1 The final for BIO201B...

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Lecture 38. (4-29-11)
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Final Exam 1. The final for BIO201B is scheduled for Tuesday (5-10-11) from 11:45 to 2:45 in Knox 20 2. The final exam will consist of the Section III exam (about 30 questions) and the lab exam (about 20 questions) together (for about 50 questions total). 4. The final exam will cover information from the lectures from March 28 (lecture #25) to the end of the course and all of the labs. 5. For examples of what the final might look like, see the final exams on UBlearns under Course Documents.
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Lab Lectures for the Final Lab #1 Lecture #8 (2-7) Lab #2 Lecture #12 (2-18) Lab #3 Lecture #18 (3-4) Lab #4 Lecture #25 (3-28) Lab #5 Lecture #29 (4-8) Lab #6 Lecture #35 (4-22)
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Announcements I will hold normal office hours next week and on Monday, 5-9-11 I will have a help session on the evening of May 9. I will announce the time and place on UBlearns For next Monday’s class (5-2-11), I will hold a review session in preparation for the final.
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Cancer
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In general, cancer cells have problems with: 1. Growth signals: A. Ignore inhibitory growth signals (tumor suppressors) B. Continue to grow in the absence of growth factors 2. Defects in mitotic checkpoint proteins 3. Eliciting an apototic response
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Cancer can cause loss of cell growth control because of mutations in: A. Tumor suppressor genes . They can’t stop unrestricted growth of genetically altered cells. They ignore inhibitory signals (like checkpoints). For example about 50% of human cancers have altered p53 B. Oncogenes: An oncogene is a gene that has the potential to cause growth without growth factors. In
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