Synapses

Synapses - At each specific synapse there are usually only...

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At each specific synapse there are usually only one type of excitatory or inhibitory receptors   Graded  = strength of post-synaptic potential will decrease over space and time because  controlled by passive diffusion   Post - passive, diffusion Pre - active, generated by opening channels   Action Potential reaches terminal = voltage gated calcium  --> vesicles release neurotransmitters    What leads to neurotransmitter release?  Calcium !   Synapses Task : 1. Produce localized and rapid signal 2. Repeatable at high frequency 3. Can be up or down regulated  => Plasticity happens at the synapse   Synapse Morphology  1. Localized - occupy very small portion of total cell membrane Dendritic Spines: augment receptive surface of the neuron and increase amount of input info  neuron can handle   Vesicles - contain neurotransmitter 1. Ready and packed for release 2. Protects from enzymatic degredation
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This note was uploaded on 04/05/2008 for the course BIOL 455 taught by Professor Sabrinaburmeister during the Spring '08 term at UNC.

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Synapses - At each specific synapse there are usually only...

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