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sol6934 - Chapter 1 1 y NA = s NA = 6.84 9.29 3.83 5.95...

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Chapter 1 1. % 95 . 33 12 . 2 24 . 6 % 25 . 31 % 100 336 . 6 98 . 1 98 . 1 4 73 . 15 1 5 ) 336 . 6 77 . 5 ( ) 336 . 6 95 . 5 ( ) 336 . 6 83 . 3 ( ) 336 . 6 29 . 9 ( ) 336 . 6 84 . 6 ( 336 . 6 5 68 . 31 5 77 . 5 95 . 5 83 . 3 29 . 9 84 . 6 2 2 2 2 2 = = = = = = = - - + - + - + - + - = = = + + + + = A A A NA NA NA cv s y cv s y Very similar levels 2. 8596 . 0 178 153 9607 . 0 178 171 2 ^ 1 ^ = = = = π π 3. risks similar very No, ) 1172 . 0 11035 1293 ) | ( ) 1153 . 0 11036 1273 ) | ( ) c B C P b B C P a = = = = 4. 74 . 139 , 75 . 23 , 18 . 94 ) 013974 . 264913 3702 ) | ( 002375 . 171363 407 ) | ( ) 009418 . ) ( ) c L C P L C P b C P a = = = = = 5. Sensitivity: 45/50 = 0.90 (90%) Specificity: 24/63 = 0.38 (38%) PV + : 45/84 = 0.54 (54%) PV - : 24/29 = 0.83 (83%) Accuracy: (45+24)/113 = 0.61 (61%) 6.
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Sensitivity: 116/140 = 0.83 (83%) Specificity: 211/215 = 0.98 (98%) PV + : 116/120 = 0.97 (97%) PV - : 211/235 = 0.90 (90%) Accuracy: (116+211)/355 = 0.92 (92%) 7. a) Cross-sectional b) Cohort study c) Randomized clinical trial d) Historical controls 8. a) Dependents: Ability to obtain erection (ordinal), EDITS (Numeric) Independent: Dose (Numeric) b) Approx. 41 c) Validity: It is accurately measuring patient satisfaction. Reliability: Reproducability of responses within subjects d) Yes Chapter 2 9. 2206 . 77 . 0 3 . 7 40 6 . 45 ) 6 . 45 ( : women for men for 99 . ) 6 . 45 ) 2 . 12 ( 33 . 2 74 ( 01 . ) 33 . 2 ( ) ) 296 , 142 ( 77 219 ) 2 . 39 ( 96 . 1 219 95 . ) 96 . 1 96 . 1 ( ) 05 . ) 5 . 99 ) 3 . 14 ( 645 . 1 123 ( 05 . ) 645 . 1 ( ) 10 . ) 8 . 162 ) 5 . 15 ( 28 . 1 143 ( 10 . ) 28 . 1 ( ) 1020 . 27 . 1 6 . 2 3 . 63 60 ) 60 ( ) 0721 . 46 . 1 8 . 2 9 . 67 72 ) 72 ( ) = = - = = = - - ± ± = + - = = - = - = + = - = - < = < = = - = Z P Y P Y P Z P g Y P f Y P Z P e Y P Z P d Z P Y P b Z P Y P a σ μ σ μ 10.
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= = = = = = = = = = = = 02 . 2 50 3 . 14 , 123 ) 00 . 1 9 0 . 3 , 9 . 69 ) 22 . 0 35 3 . 1 , 9 . 33 ) 56 . 0 25 8 . 2 , 9 . 67 ) Y Y Y Y Y Y Y Y N d N c N b N a σ μ σ μ σ μ σ μ 11. 1611 . 99 . 0 02 . 2 123 125 ) 125 ( ) 6802 . 1841 . 1357 . 1 ) 1 . 1 9 . 0 ( 1 9 . 69 71 1 9 . 69 69 ) 71 69 ( ) 0 64 . 8 22 . 0 9 . 33 32 ) 32 ( ) 0010 . ) 09 . 3 ( 75 . 3 56 . 0 9 . 67 70 ) 70 ( ) = = - = = - - = - = - - = = - = = < = - = Z P Y P d Z P Z P Y P c Z P Y P b Z P Z P Y P a Chapter 3 12. exist s difference , hypothesis null Reject the : Conclusion 002 . ) 0010 (. 2 ) 33 . 3 | 33 . 3 | ( 2 : 96 . 1 | | : 33 . 3 4 . 2 0 . 8 36 ) 43 . 12 ( 37 ) 54 . 7 ( 6 . 38 6 . 30 : 0 : 0 : 025 . 2 / 05 . 2 2 2 1 2 1 0 = < = - = = - = - = + - = - = - Z P P z z z RR z TS H H obs obs A μ μ μ μ 13.
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POMS reduces fluoxetine conclude t don' , hypothesis null Reject the to Fail : Conclusion .05 and 10 . ) 43 . 1 ( : 725 . 1 | | : 43 . 1 21 . 3 58 . 4 9 ) 67 . 8 ( 13 ) 07 . 5 ( 89 . 44 31 . 40 : 0 : 0 : 20 , 05 . 2 9 13 , 05 . 2 2 2 1 2 1 0 < - - = - = - - = - = + - = < - = - - + t P P t t t RR t TS H H obs obs A μ μ μ μ 14. Healthy MAT H Rank Pre-Tran MAT PT Rank 5.36 14 2.64 5 4.35 11 4.84 13 2.61 4 2.42 2.5 3.78 10 2.92 7 2.78 6 2.94 8 4.51 12 2.42 2.5 3.43 9 15.08 16 1.66 1 11.04 15 67 69 Since both T 1 (67) and T 2 (69) are above 49, do not conclude population means (or medians) differ. 15. 0 ) 73 . 10 ( : 860 . 1 : 73 . 10 87 . 0 3 . 9 9 / 6 . 2 3 . 9 : 8 , 05 . = = = = t P P t t RR t TS obs obs 16. a. 132 . 2 : 99 . 1 5 / 02 . 2 8 . 1 : Poor 30 . 3 5 / 51 . 2 7 . 3 : Extensive 4 , 05 . = = = = = t t RR t t obs obs obs Since extensive metabolizers are significant, may be evidence that codeine is cause b.
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306 . 2 | :| 82 . 2 70 . 4 22 . 13 5 ) 15 . 0 ( 5 ) 5 . 10 ( 68 . 0 9 . 13 : : Morphine 306 . 2 | :| 60 . 1 4 . 66 106 5 ) 114 ( 5 ) 95 ( 558 664 : : Codeine 8 , 025 . 2 5 5 , 2 / 05 . 2 2 8 , 025 . 2 5 5 , 2 / 05 . 2 2 = = = = + - = = = = = + - = - + - + t t t RR t TS t t t RR t TS obs obs obs obs Codeine not significantly different. Morphine is significantly different 17.
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