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StudyGuideforBC511Final

StudyGuideforBC511Final - Study Guide for Final(BC511...

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Study Guide for Final (BC511 Summer) Note: This is only a very brief overview of the topics that will be covered on the exam. These are things that I feel are important, and are more or less classic biochemistry problems. There may be specifics I have forgotten to mention. As always, anything that was mentioned in the class or that is in your notes is fair game for the exam. BUT DON’T GET TOO BOGGED DOWN BY INANE DETAILS! You should also recognize some of the principles and ideas from the first term that were reemphasized in the second portion of the class. General topic guideline for the Final. The following are topics you should really have a good grasp of for the final. You should also know the purpose and principles behind each of them. At this point all of you should have a general idea of the “big picture” of how life works – biochemically – and be able to recognize the profound connections between some of these basic metabolic pathways. - Free Energy Problems - Glycolysis - The TCA (Krebs) cycle - Glycogen Phosphorylation and Glycogen Synthesis (know especially how these processes work and the regulation of these paths) - Gluconeogenesis - Pentose Phosphate Pathway including knowing how transaldolase and transketolase works - Urea Cycle - Fatty Acid Biosynthesis and Fatty Acid Breakdown (I would especially know HOW the initiation and propogation steps happen) - Electron Transport and Oxidative Phosphorylation (especially some of the key details about the complexes and the ATP synthase) - Nucleic Acids (This was only briefly covered but you should especially know the structures). - You should also have a good understanding of the prosthetic groups and coenzymes involved in some of the key reactions in metabolism. Refer to Chapter 7 to refresh yourself on these groups. These include: NAD/NADP, FAD, CoA, TPP (Thiamine Pyrophosphate), Pyrodoxal Phosphate, Biotin, Tetrahydrofolate (THF), Cobalamin, Ubiquinone, and Cytochromes. Each of
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