# test3sp07 - Print Test

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Print Test https://www.casa.uh.edu/CourseWare/Root/UsersStudents/PrintTest.htm 1 of 9 4/22/07 2:31 PM Test 3 You scored 90 out of 100 Question 1 Your answer is CORRECT. A sample of 20 European Americans, 19 African Americans and one male chimpanzee were genotyped for the SLC26A3 locus. The study revealed 2 synonymous and 4 nonsynonymous polymorphisms within humans. If there are 15 synonymous differences fixed among humans and chimpanzees, how many nonsynonymous differences are expected to be fixed among these species if the gene has evolved according to the neutral theory? a) 60 b) 1 c) 0 d) 30 e) 15 Question 2 Your answer is CORRECT. Two loci in Tribolium castaneum , A and B, have two alleles each (A/a and B/b, respectively). In a North American population, the A allele has a frequency of 0.18 , the B allele has a frequency of 0.53 , and the AB haplotype has a frequency of 0.12 . Assuming that the coefficient of linkage disequilibrium in the following generation is D = 0.018 , calculate the genetic distance between the A and B loci in cM. (See formula sheet.) a) 17 b) 25 c) 8 d) 20 e) 53 Question 3 Your answer is CORRECT. According to Fisher's fundamental theorem of natural selection, how is the additive genetic variance for fitness expected to change as a population approaches equilibrium? (See formula sheet.) a) It should increase if it is under positive selection and decrease if it is under negative selection b) It should decrease if it is under directional selection and increase if it is under stabilizing or disruptive selection c) It should not change d) It should decrease if it is under positive selection and increase if it is under negative selection 30 = 15*(4/2) In the current generation we have: D=0.12*0.41-0.06*0.41=0.0246 Since D'=0.018 and D'=D(1-r) r=1-0.018/0.024=0.25 Correct answers are marked by a

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