Week 4-July 21-annotated

Week 4-July 21-annotated - Week 4 July 21, 2011 Acidity of...

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Unformatted text preview: Week 4 July 21, 2011 Acidity of Carboxylic Acids • Draw some examples of carboxylic acids. Why are they acidic? What is a typical p K a ? • For each of the following carboxylic acids, change the structure slightly so that the acid becomes more acidic . Explain why that change is effective. OH O OH O F OH O • For each of the following carboxylic acids, change the structure slightly so that the acid becomes less acidic . Explain why that change is effective. OH O F OH O Reading : Sections 20.1 and 20.4 39 Week 4 July 21, 2011 Carboxylic Acid Derivatives • Draw some examples of each of the following carboxylic acid derivatives: ester (and lactone) amide (and lactam) acid chloride acid anhydride nitrile Reading : Section 21.1 40 Week 4 July 21, 2011 Some Syntheses of Carboxylic Acids and Nitriles • You already know some ways of making carboxylic acids. What are they? • Here’s another way of making a carboxylic acid. Can you draw the mechanism? What is special about this method for making carboxylic acids?...
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This note was uploaded on 07/28/2011 for the course CHEM S20 taught by Professor Evan during the Spring '11 term at Belhaven.

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Week 4-July 21-annotated - Week 4 July 21, 2011 Acidity of...

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