96ex2 - Student name_ AGR 3303 - Genetics University of...

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Student name_______________________________ AGR 3303 - Genetics 24 Oct 1996 University of Florida - Fort Lauderdale Hourly exam #2: MOLECULAR GENETICS Multiple choice (60 pts.) Please read these carefully . One and only one response (a, b, c, d, or e) completely and correctly answers the question, or completes the statement. Circle the appropriate response ON THE SEPARATE ANSWER SHEET and keep this exam. Make sure your circle is unambiguous. Take time to relax. 1. Which of the following is a nucleotide of DNA: a. deoxyribose + guanine + phosphate group b. deoxyribose + uracil + phosphate group c. ribose + pyrimidine + phosphate group d. deoxyribose + nitrogenous base e. none of the above 2. A gene has both a normal form and an abnormal form. The abnormal form of the gene produces an abnormal polypeptide, which disables the function of the resulting monomeric enzyme. Why would heterozygotes (individuals with a normal copy and an abnormal copy of the gene) be functionally normal? a. because normal polypeptides would join together 25% of the time b. because of the limited correction due to frameshift mutations c. because enzymes can be effective in partial amounts d. because of diffusible substances e. none of the above 3. Translation: a. involves highly repetitive DNA b. produces ribosomal rRNA c. produces polypeptide d. occurs in the nucleus e. produces tRNA 4. DNA is recovered from an orc, believed to be a fearsome species of goblin. The DNA contains the following composition of bases: adenine 16%, guanine 33%, thymine 17%, cytosine 34%. The orcs most likely have: a. double-stranded DNA b. double-stranded RNA
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c. single-stranded DNA d. single-stranded RNA e. a bad case of nausea following trick-or-treat 5. The Central Dogma examines which characteristic of the genetic material? a. replication b. mutation c. expression d. storage e. dominance 6. Watson and Crick (1953) proposed: a. the genetic code b. the double-helix model of DNA c. the polymerase chain reaction d. that DNA is the hereditary molecule e. the Central Dogma 7. Which statement is true of the double helix? a. heating causes the strands to denature b. GC pairs involve three hydrogen bonds c. purine pairs with pyrimidine d. all of the above e. none of the above 8. Human insulin can be produced by bacteria, using human DNA. This proves that: a. the genetic code is a heteropolymer specifying a single amino acid b. a new amino acid is transcribed from a nonsense mutation c. avirulent bacteria can be rendered infectious with exogenous DNA d. bacteria and humans must have similar coding dictionaries e. translation requires oligomeric proteins homologous to ribosomal tRNA 9. The human genetic disease phenylketonuria (PKU) can result in
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96ex2 - Student name_ AGR 3303 - Genetics University of...

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