BMS635Syll - BMS 635 Structural Molecular Biology Spring...

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Schedule and location CMS 5 th floor conference room (Rm 5112). Mon & Wed 10:30 am – 12:00 pm. Syllabus Followed by a short introduction, the course is divided into three blocks according to the principle methods discussed and biological/functional issues addressed: Course overview, introduction and objectives. Bioinformatics profiling. (i) Low to medium resolution methods. Optical, spectroscopic and scattering methods Optical methods and sophisticated imaging techniques using high-end light and electron microscopy, laser microsurgery for structural and functional studies of cells, organelles and other large assemblies associated with malignant tumours. Circular dichroism and fluorescence spectroscopy to determine overall fold and structural integrity of disease-related proteins. Small angle X-ray scattering, analytical ultracentrifugation and dynamic light scattering to study the oligomeric state and the polydispersity of biological macromolecules and assemblies from human pathogens or abberant forms found in
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BMS635Syll - BMS 635 Structural Molecular Biology Spring...

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