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plugin-Chapter 5 Students - Experiments, Good and Bad...

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CHAPTER 5 Experiments, Good and Bad
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THOUGHT QUESTION 1 In research to determine the relationship between two conditions (activities, traits, etc.), one of them is often defined as the explanatory (independent) variable and the other as the outcome or response (dependent) variable . In an experiment to determine whether the drug memantine improves cognition of patients with moderate to severe Alzheimer’s disease, whether or not the patient received memantine is one variable, and cognitive score is the other. Which is the explanatory variable and which is the response variable?
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THOUGHT QUESTION 2 In testing the effect of memantine on the cognition of Alzheimer’s disease patients (from TQ #1), how would you go about randomizing 100 patients to the two treatment groups (memantine group & placebo group)? Why is it necessary to randomly assign the subjects, rather than having the experimenter decide which patients should get which treatment?
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TALKING ABOUT EXPERIMENTS So far we have mainly talked about observational studies (e.g., sample surveys). An experiment takes the opposite approach by imposing some treatment in order to see what happens. Carefully designed experiments allow us the opportunity to make conclusions about cause-and- effect relationships, while observational studies can only identify associations, but not causation.
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VOCABULARY OF EXPERIMENTS An explanatory variable is a variable that we think explains or causes changes in the response variable. A response variable is a variable that measures an outcome or result of an experiment. For example: An experiment might be interested in how the explanatory variable exercise affects the response variable blood pressure.
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VOCABULARY OF EXPERIMENTS Subjects are the individuals studied in an experiment. A treatment
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plugin-Chapter 5 Students - Experiments, Good and Bad...

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