Intro and Chptr 1 - APK 2105: APPLIED HUMAN PHYSIOLOGY...

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Unformatted text preview: APK 2105: APPLIED HUMAN PHYSIOLOGY Contact Info Dr. John Dobson Email: [email protected] Office: 156 B FLG, 392-0584 ext 1332 Office Hours: T: 9:30-12:00 Th: 9:30-12:00 Or by appointment Class Website – E-Learning in Sakai • You must have a GatorLink username and password. If you don't, call 392-help or [email protected] 392• Go to: • • • • In the top right corner you will see the “Login” link Enter your Gatorlink ID and password You will then enter your “My Workspace” page Across the top (banner) of the page you will see the link for this course (i.e., APK 2105). • If you have log in or other problems, seek assistance at the UF Computing Help Desk 392-4357 [email protected] Page 1 Class Meetings • Lecture meets each day, Lab meets some days… • Lecture class meetings: When: EARLY!!!! Please don’t blame me, I didn’t choose this class period. What: Powerpoint lectures, except for exam days. Your responsibilities: - attend lectures - take notes - ASK and ANSWER QUESTIONS Lecture Notes • Posted on the class website in E-Learning in Sakai • Please make sure to print off and use these notes during class (they are also the best way to study for your exams). • In order to view and print these notes, you will need to have a current version of the Adobe Acrobat Reader. You can get a (free) copy of this Reader at Additional Course Materials MANDATORY: – APK 2105 Human Physiology Lab Manual With Activities From PhysioEX 8.0. Benjamin Cummings. Latest version. STRONGLY ENCOURAGED: - Principles of Human Physiology latest ed. Stanfield and Germann Needed to help prepare for lecture exams. Needed to help with lab assignments. If you purchase a new copy of 4th edition of the text, and then follow the instructions on registering for the “Physiology Place,” you can access useful physiology animations and pictures. Page 2 Course Grading Scheme YOU WILL BE EVALUATED ON THE FOLLOWING BASIS: Exams (4) Lab Reports (5) Lab CD-Rom Assessments (7) CDLab Final (1) Total points 65 10 14 11 100 points (14, 17, 17, 17 points) points (5 reports x 2 points each) points (7 assessments x 2 points each) points points EXAMINATIONS EXAMINATIONS • Four examinations, each will contain approximately 50-60 true/false and multiple 50choice questions. • You will have 1 week following the return of an exam to appeal the grade. Appeals must be in writing. _______________________________________ • In class exam review ?????, if time permits. Please ask questions during class! Please ask questions after class! Please come to my office and ask questions! 90 85 M e a n E x a m S c ore 80 75 70 65 60 < 3 Lectures 2 Lectures/month 1 Lecture/week Almost all Classes Missed Page 3 Practice Exams • Not associated with any course credit, they are simply meant to help you prepare for the lecture exams • One practice exam for each of the four lecture exams. Each consists of 10 true-false and multiple choice questions. true• Each practice exam will become available exactly 48 hours before the corresponding lecture exam. • May retake the exams as many times as you like…. • Suggest you wait until after you have studied and think you know the material fairly well….. Lab Information • Your lab teaching assistant will describe the lab procedures and assignments in greater detail during your first lab meeting. For • Lab attendance is mandatory. For each lab meeting missed, 3 POINTS will be DEDUCTED POINTS DEDUCTED from your FINAL CLASS SCORE. FINAL • The only exceptions to the above rule will be those absences that are completely unexpected and have been documented in writing by a physician, court official, etc. Grading Scale A = 90.0 - 100 B+ = 87.5 - 89.9 B = 80.0 - 87.4 C+ = 77.5 - 79.9 C = 70.0 - 77.4 D+ = 67.5 - 69.9 D = 60.0 - 67.4 E < 59.9 Page 4 Words of Wisdom • If you get a 89.99 you will get a B+, not an A, etc…… • As microeconomics professor Mark Rush says, As microeconomics professor Mark Rush says "If this happens to you, it's obviously unfair. And, in fact, I will grieve with you, I will rail against the total injustice of it with you, I will even raise my voice to the heavens and proclaim how unfair it is with you. But: I WILL NOT CHANGE YOUR GRADE." MakeMake-Up Work • Only work missed as a result of a documented excused absence will be given consideration without penalty. It is the student's responsibility to contact the instructor if a make-up is necessary. • For unexcused absences in which you miss an exam or unexcused absences in which you miss an exam or another assignment, you will be penalized 15% per day. • See me prior to the start of this course if you participate in an activity that may cause a problem with attendance (e.g. varsity sports). If for personal or medical reasons several classes are missed, the instructor should be informed of the reason. Honor Policy • The University policy on academic honesty is clear and reads as follows: “We the members of the University of Florida Community, pledge ourselves and our peers to the highest standard of honesty and integrity." • This includes ALL COURSE EXAMS, REPORTS, ALL ASSIGNMENTS and ASSESSMENTS! Note: It is also Note considered an honor violation for students to purchase, honor use, and/or possess previously USED class Lab use and/or possess previously USED class Lab Manuals. Manuals. It will also be considered a violation if you work with another student on the PhysioEX experiments or pertinent assessments. • Students violating this policy will be sanctioned according to the Committee on Student Conduct, receive a grade penalty for the course or some other penalty for failure to abide by this standard of conduct. Page 5 Date Class Topic Chapter May 9 Course Intro and Cell Structure and Function 1,2 10 & 11 Cell Structure and Function 12 & 13 Cell Metabolism 3 May 16 Exam #1 1, 2, 3 17 & 18 2 Membrane Transport 4 19 & 20 Endocrine Function 5,6 23 Regulation of Metabolism 21 24 & 25 Nerve Cells and Electrical Signaling 7 May 26 Exam #2 4, 5, 6,7, 21 27 Synaptic Transmission + Neural Integration 8 31 Selected Nervous System Topics 9, 10, 11 June 1 & 2 Muscle Physiology 12 3 Cardiac Function 13 6&7 Blood Flow, Vessels & Pressure 14 June 8 Exam #3 8-14 9 Blood 15 10 Ventilation 13 & 14 Gas Exchange + Regulation of Breathing 17 15 Renal Function 18 16 Fluid and Electrolyte Balance 19 June 15 or 16 Lab Final Exam - During Last Lab Meeting --- June 17 Final Lecture Exam 15-19 DATES May 9-10 May 11-12 May 13 May 16-17 May 18-19 LAB ITEM Introduction and Histology Lab Enzyme Kinetics Lab PhysioEX Activity I - Histology (E-Learning assessment opens on 5/11 at 8:00 am Friday - No Lab PhysioEX Activity II - Cell Transport (E-Learning assessment opens 5/16 at 8:00 am) PhysioEX Activity III - Endocrine (E-Learning assessment opens 5/18 at 8:00 am) May 20 Friday - No Lab May 23-24 Metabolism Lab PhysioEX Activity IV - Neurophysiology (E-Learning assessment opens 5/23 at 8:00 am) May 25-26 No Lab May 27 Friday - No Lab PhysioEX Activity V - Skeletal Muscle (E-Learning assessment 5/30 at 8:00 am) Cardiovascular Lab PhysioEX Activity VI - Cardio. Dynamics (E-Learning assessment opens 6/1 at 8:00 am) 30- 31 June 1-2 June 3 Friday - No Lab June 6-7 June 8-9 June 10 Acid-Base Lab Pulmonary Function Lab Friday - No Lab Lab Review PhysioEX Activity VII - Renal (E-Learning assessment opens 6/13 at 8:00 am) June 13-14 June 15-16 Lab Final Exam – During Last Lab 16 BACKGROUND S = Stanfield Text (3rd ed) P = PhysioEx section of the Lab Manual -----------S 56-72, 83-86 LM 63-73 S, internet, etc. ------------ ASSIGNMENT DUE ----------------------- E-Learning assessment I closes Friday 5/13 5:00 pm LM 75-89 LM 91-109 -----------S 604-612,343-347 LM 111-122 ----------------------LM 123-135 S 360-371, 396-428 LM 137-149 -----------S 70-72, 500-501, 556-563 S 452-472, 476-503 ------------ E-Learning assessment II closes Wed 5/18 5:00 pm E-Learning assessment III closes Fri 5/20 5:00 pm Enzyme Lab Report E-Learning assessment IV closes Wed assessment IV closes Wed 5/25 5:00 pm --------------------Metabolism Lab Report E-Learning assessment V closes Wed 6/1 5:00 pm E-Learning assessment VI closes Fri 6/3 5:00 pm Cardiovascular Lab Report Acid-Base Lab Report -----------Pulmonary Lab Report LM 151-161 ------------ E-Learning assessment VII closes Wed 6/15 5:00 pm Pertains to “wet labs” that are conducted in FLG room 107 D or E. Pertains to “PhysioEx” labs that are conducted on your own Selected Comments About Lab…. • “Wet” lab classes will today. • Lab classes meet in FLG 107 D and E • Make sure you are prepared for the first meeting: - Purchase and bring the Lab Manual Page 6 PhysioEx Activities • Throughout the semester you will complete seven different PhysioEx activities using the pertinent book and CD-ROM. Each activity has a CDpertinent E-Learning assessment. E- • The first PhysioEx activity is the Histology Supplement. • You will need to use your Stanfield textbook, as well as additional resources such as an anatomy book and/or the internet to answer resources such as an anatomy book and/or the internet, to answer the the questions in that activity. • The remaining six PhysioEx activities will not require you to consult external resources (e.g. your textbook, the internet, etc.). Instead, each of those remaining six activities will guide you through a series of virtual lab experiments that you will use to generate data. • You will then use that data to answer the pertinent PhysioEx and EELearning questions. Heads Heads Up!!!!! • The Histology Review assessment opens this Wed 5/11 at 8:00am and closes Friday 5/13 at 5:00pm. • First complete the questions in the Histology Review Supplement section at the end of your Lab Manual. • You will need to use your Stanfield textbook, as well as St additional additional resources such as an anatomy book and/or the internet, internet, to answer the questions in that activity. • Once you have completed those pertinent questions, you will then demonstrate your knowledge for a grade by answering those very same questions in the pertinent E-Learning Eassessment. [Note: the assessment, not the PhysioEx activity, is the thing that closes at 5:00pm on Friday 5/13]. Class Preface Scientific Method • Question? • Look for the answer - Review the literature • Develop a testable hypothesis • Design experiments to test the hypothesis • Collect data • Analyze data • Accept or reject the hypothesis • Develop theory Page 7 Intro I -The Internal Environment • Fluid Compartments: about 60% of body weight is water 1. Intracellular Volume (~27 liters) 2. Interstitial Volume (~12 liters) 3. Plasma Volume (~3 liters) • Cellular Compartments: Phospholipid bilayer separates 1. Intracellular – lots of potassium, magnesium, phosphate. of potassium magnesium phosphate 2. Extracellular – sodium, chloride, bicarbonate, oxygen, glucose, etc. • Cells: 100 trillion (100,000,000,000,000 – WOW!) There are over 200 types of cells, but only four major types: 1. 2. 3. 4. Neurons Muscle Cells Epithelial Cells Connective Tissue Cells Intro II - Homeostasis • The regulatory mechanisms of the body can be understood in terms of a single, shared function: that of maintaining constancy of the internal environment. • A state of relative constancy is maintained by effectors that are regulated by sensory “devices.” Page 8 Biological Control Systems A series of interconnected components that maintain a physical or chemical parameter near a constant value. Requires: 1. 1. 2. Receptor – excited by a stimulus Integrating Center (CNS, Endocrine) - receive stimulus - assesses strength - responds either + or - 3. Effector – corrects disturbance Biological Control System - Example Failure of a biological control system results in disease! Negative Feedback Control Often involves: Antagonistic Effectors (“push-pull”) – Increasing activity of one effector is accompanied by decreasing activity of an antagonistic effector decreasing activity of an antagonistic effector. – Affords a finer degree of control as in body temperature regulation. Multiple and Redundant Systems Page 9 Positive Feedback Control The action of effector amplifies the action of the stimulation. + Page 10 ...
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This note was uploaded on 08/05/2011 for the course APK 2105 taught by Professor Brooks during the Summer '07 term at University of Florida.

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