Chem 30CL-Lecture 5a

Chem 30CL-Lecture 5a - Lecture 5a Click to edit Master...

Info icon This preview shows pages 1–5. Sign up to view the full content.

View Full Document Right Arrow Icon
Click to edit Master subtitle style 8/6/11 Mass spectrometry Lecture 5a
Image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
8/6/11 J. J. Thompson was able to separate two neon isotopes (Ne-20 and Ne-33) in 1913 (Noble Prize 1906, Physics, for the discovery of the electron) H. Dehmelt, W. Paul (Noble Prize 1989, Physics) built the first quadrupole mass spectrometer in 1953. K. Tanaka, J.B. Fenn (Noble Prize 2002, Chemistry) developed the electrospray and soft laser desorption method which are used for a lot of proteins History
Image of page 2
8/6/11 EI is hard ionization technique An ionizing beam of electrons generated in the ionization chamber causes the ionization and/or fragmentation of the molecule The higher the energy of the electrons is, the more fragmentation is observed up to the point where the molecular ion (M+) cannot be observed anymore Electron Impact Mass Spectrometry I Inlet vacuum Detector cathode anode 70 eV Magnetic Field (H) Sample Chamber Ionizing Chamber accelerator plates e - AB AB AB + AB + AB + AB + AB + AB + A + A + B + B + B +
Image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
8/6/11
Image of page 4
Image of page 5
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern