RQ8 - CHEN 4820 Reading Quiz RQ8 Harrison sec 7.0 7.4 and...

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CHEN 4820 Reading Quiz RQ8 Harrison sec 7.0 – 7.4 and Scopes sec 5.1 and 5.2 (liquid chromatography and adsorption theory) Pledge: On my honor, I have neither given nor received aid on this quiz. Print name: _________________________________________ Signature: __________________________________________ Quiz: Q1. Write “A” next to the statement if it is true for analytical chromatography. Write “P” next to the statement if it is true for production chromatography. 1. Aim is to identify the presence of a solute and determine its concentration. 2. Aim is to generate a product that meets predetermined targets for purity and cost. 3. Strives for “baseline resolution” of solutes through low column loading (mass solute/volume resin) so that the adsorption approximates a linear isotherm. 4. Operates at high column loading to achieve lower cost at the expense of poorer resolution. Therefore, accepts the complications a nonlinear isotherm brings: the solute migration speed changes with solute concentration. 5. Typically uses larger resin bead size and resin with higher binding capacity. 6. Typically uses smaller resin bead size and accepts resin with lower binding capacity in exchange for stability at extreme column pressure. A1.
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This note was uploaded on 08/10/2011 for the course CHEN 4820 at Colorado.

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RQ8 - CHEN 4820 Reading Quiz RQ8 Harrison sec 7.0 7.4 and...

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