01.11.10 - alert microphages to attack the foreign body or...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
Jan 11 th Infectious disease in INDIVIDUALS VS. POPULATION studied by 2 sciences EPIDEMIOLOGY AND PATHOLOGY Encounter filter – exposure; epidemiology is the study of incidence and spread; access to treated water prevents exposure to water-borne disease limiting exposure and spread. Compatibility filter – ability of disease to infect host; zoophilic mosquitos prefer animals over humans generally in NA because humans migrated to the continent only 12 thousand years ago thus mosquitos evolved preying upon animals. Lysosomes in saliva. Nitrogen in human body is not a free protein – protection against bacteria by limiting nutrients, thus suppressing reproduction. ARMS RACE BTWN HOST AND PARASITE Proteases activated in blood when there is a wound or infection. Binds to bacteria and acts as a red flag to
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: alert microphages to attack the foreign body or eats the bacteria themselves – disrupting the bacteria membrane. Interferon stimulates natural killers. Inflammation – human body is trying to localize infection – red, hot, swollen, painful Environmental stability – how long an agent can persist in the environment. Goal to reduce Ro to less than 1 to avoid epidemic; reduce transmission, reduce pathogen replication, prevent pathogen access to water. Pathogens manipulate host to increase spreading. Lethal factor and edema factor enter macrophage cells – goal to kill host to enable transmission of spores through decay. Cystic Fibrosis may have arose as a resistant form to cholera....
View Full Document

This note was uploaded on 08/10/2011 for the course PARA 515 taught by Professor Timothygeary during the Winter '10 term at McGill.

Ask a homework question - tutors are online