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01.20.10 - Jan 20th Bacteria found in biofilms(not free...

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Jan 20 th Bacteria – found in biofilms (not free floating), can think of biofilms as an ecosystem: they form complex structures Biofilms – dominant form of bacteria life form. More than 80% of infections in the Western World involve biofilms. Bacterial biofilms are resistant to antibiotics and immune system and UV and pH. Cells attach to surface embedded in self-made polymeric matrix. Protected from: dessication, ultra-violet light, predation and parasitism, antimicrobials (such as funghi). 1000-fold resistance compared to individuals. Formation- takes days to form. Grow on surfaces attach with food. Matrix populated by clumps of microbes, it is a community structure that evolves over time Non-dividing cells are resistant to our drugs – have variations in genetic expression between fast/slow growing. Evolve- to make use of residuals of other animals. Sequencing bacterial DNA gives higher numbers for species lists than identifying them by physiological characters and taxonomic keys – because we don’t know all species variations.
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