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LS_2_Lec_10_Muscles

LS_2_Lec_10_Muscles - Life Sciences 2 Chapter 48...

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Life Sciences 2 Chapter 48 Musculoskeletal Systems Dr. Jospeh Esdin Neural Pathway Skin receptors Sensory neuron Interneuron Motor neuron Effector
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Classification of Muscles Muscles are contractile tissue 3 types – Skeletal (voluntary) – Smooth (involuntary) – Cardiac (involuntary) Skeletal Muscles Each muscle in the body is classified as an organ A muscle is made of many fascicles Fascicles are made of muscle fibers Muscles fibers are made of myofibrils Myofibrils are contractile proteins
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Levels of Organization Fascicle Muscle Muscle fiber Sarcomere Each myofibril is made of functional units of contraction called sarcomeres Each sarcomere is bound by a network of interconnecting proteins called Z lines Thick filaments are composed of a contractile protein (myosin) Levels of Organization in Skeletal Muscles
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Levels of Organization in Skeletal Muscles Thin filaments contain a contractile protein (actin) and two regulatory proteins (troponin) and (tropomyosin) Sarcomere Thick filament Thin filaments Z line
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Thick filament Myosin Actin Thin filament Filaments Troponin Tropomyosin Thick Filaments Thick filament Myosin molecules Myosin head Myosin tail Actin binding site ATP binding site [ Cross bridge
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Thick Filaments Each thick filament is made of arranged myosin molecules Each myosin molecule is made of two heads and two tails Each myosin head contains an actin binding site and an ATP binding site Thin Filaments Thin filaments are made of three proteins Actin, troponin, & tropomyosin
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