Final Key

Final Key - CHEM 114B Final 2011 Last Name, First Name...

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CHEM 114B Final 2011 Last Name, First Name Student ID Section Number Page 1 CHEM 114B Final Exam 3:00pm- 5:59pm March 18, 2011 Write your name and student ID on EVERY page of the exam Fill in the bubbles for your student ID on the scantron. Use the number ‘1’ in place of ‘A’ or ‘U’ in your student ID (e.g. if your ID is A1234567, fill in 11234567) By signing below, I authorize Dr. Wang to leave my exam out for pick-up outside of Urey Hall 4254. I understand that my exam will be available for public scrutiny, and may be stolen. _______________________________________ Questions 1-50 Multiple Choice _________ out of 150 points Questions 51-60 Short Answer _________ out of 60 points Total _________ out of 210 points
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CHEM 114B Final 2011 Last Name, First Name Student ID Section Number Page 2 Questions 1-50 (3 pts. each): Multiple choice 1. (3 pts.) Given that the standard reduction potential of oxaloacetate is –0.166 V and the standard reduction potential of NAD + is –0.315 V. What is the  ' for the oxidation of malate by NAD + : Malate + NAD + Oxaloacetate + NADH + H + A) –4.81 V B) + 4.81 V C) –0.149 V D) +0.149 V E) +0.0523 V Answer: C 2. (3pts.) In eukaryotes, the enzymes that catalyze the reactions of glycolysis are located in: A) the cell nucleus. B) the endoplasmic reticulum. C) the mitochondria. D) the lysosomes. E) the cytosol. Answer: E 3. (3pts.) What reaction is catalyzed by aldolase? A) isomerization of DHAP to GAP B) ligation of GAP and DHAP C) reversible cleavage of F-1,6-BP to DHAP and GAP D) cleavage of DHAP to GAP E) irreversible aldol condensation of DHAP and GAP Answer: C 4. (3pts.) Which of the carrier molecules carries CO 2 ? A) NADH B) coenzyme A C) Tetrahydrofolate D) biotin E) S-Adenosylmethionine Answer: D 5. (3pts.) Some individuals have a genetic mutation of the enzyme triose phosphate isomerase (TIM) and the enzyme completely loses its function. In these individuals, how many NADH molecules are produced by glycolysis? A) 0 B) 1 C) 2
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CHEM 114B Final 2011 Last Name, First Name Student ID Section Number Page 3 D) 3 E) 4 Answer: B 6. (3pts.) Which metabolic conversion in gluconeogenesis is NOT affected by inhibiting malate transporter in the mitochondrial membrane? A) pyruvate oxaloacetate B) oxaloacetate phosphoenolpyruvate C) phosphoenolpyruvate 2-Phosphoglycerate D) 1,3-Bisphosphoglycerate glyceraldehyde-3-phosphate E) None of the above. Answer: A 7. (3pts.) NADH is generated in which step(s) of the citric acid cycle? 1) oxaloacetate + acetyl-CoA citrate 2) fumurate L-Malate 3) -Ketoglutarate succinyl-CoA 4) succinyl-CoA succinate 5) L-Malate oxaloacetate A) 1 B) 2 and 4 C) 3 and 5 D) all of above E) none of above Answer: C 8. (3pts.) If acetyl-CoA labeled with 14 C, as shown in the figure to the right, were used as the substrate for the citric acid cycle, which of the following intermediates would be produced during the first round of the cycle? A) O 2 C C C CO 2 OH H H CH 2 CO 2 * B) * O 2 C C C CO 2 OH H H CH 2 CO 2 C) CoAS C CH 3 O *
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CHEM 114B Final 2011 Last Name, First Name Student ID Section Number Page 4 O 2 C C C CO 2 OH H H CH 2 CO 2 * D) * O 2 C C C CO 2 OH H H CH 2 CO 2 E) O 2 C C C CO 2 OH H H CH 2 CO 2 * Answer: B 9. (3pts.) Cori cycle consists of
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Final Key - CHEM 114B Final 2011 Last Name, First Name...

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