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Unformatted text preview: Practice questions representative of those that will be included in exam 2 1. Which of the following is NOT an example of a phenomenon showing epigenetic inheritance? a. Position effect variegation b. Catabolite repression c. X‐inactivation d. Paternal imprinting e. Maternal imprinting 2. Which of the following is NOT associated with X‐inactivation? a. Inactivation based on parental origin b. Random inactivation c. XIST d. Barr body e. Mosaic pattern of the female calico cat 3. Which of the following is common to X‐inactivation and genetic imprinting? a. Resetting in the germline b. Epigenetic inheritance c. Methylation d. Histone acetylation e. All of the above 4. Which of the following are false about epigenetic inheritance? a) Results in a 9:3:3:1 ratio in crosses b) Is due to methylation c) Occurs only when the DNA sequence as well as the chromatin structure are faithfully inherited d) Causes calico cats to be multicolored 6) The Drosophila gene 'eyeless' and the mouse gene 'Pax 6' a) are involved in specifying eye development b) Are gap genes c) Have sequences that are not related d) Are required for head development 7. Establishment of the dorsal‐ventral axis of the Drosophila embryo: a) involves the production of localized DL mRNA on the ventral side of the developing embryo. b) Occurs via a maternal signal c) Involves the zygotically expressed DL morphogen. d) Depends on the activity of anterior‐posterior morphogens, such as BCD or HB‐M. e) None of the above. 8) Because one of the two X chromosome in mammals is randomly inactivated, female individuals are a) mosaics for different alleles on the X chromosome b) unbalanced c) showing imprinting d) having smaller X‐chromosomes 9 In eukaryotes, which of these factors guides the RNA polymerase to the transcription start site? a) Poly A binding proteins b) TATA binding protein c) snRNA2 d) rho factor 10 The conserved ATATAA sequence located at ‐30 is a) a part of the newly formed mRNA b) a part of the eukaryotic promoter c) a part of the prokaryotic promoter d) a ribosome entry site Solutions: 1b 2a 3e 4a 6a 7b 8a 9b 10b ...
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- Spring '08