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Lecture 16a - An Overview of Addictive Processes As...

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1 An Overview of Addictive Processes As individuals interacting in our environments we engage in motivated adaptive behaviors . Types of motivations: Biological motivations (e.g. food & sex) Cognitive/experiential motivations (e.g., relationships) Activation of Behavior (under normal non-drug circumstances): Structures: NAc and Amygdala – whether a stimulus is motivating Prefrontal Cortex – salience of the motivation & intensity of the behavioral response DA from VTA: Motivationally relevant event DA release all structures in motive circuit Novel event DA release (repeated exposure no further DA release) Cues associated with motivating events DA release 1. Alert organism of a novel salient stimulus 2. Alert organism of a pending familiar motivational stimulus What does dopamine actually do?
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2 An Overview of Addictive Processes (continued) With drug use….. Amygdala – Important for learning associations between motivating stimuli and otherwise
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