Unformatted text preview: Experiment: Label LDLs with ferretin or 125-Iodine isotope. Add equal concentration of labeled LDLs to fibroblast cultures from normal and FH-individuals Allow equal time for binding; wash away any unbound LDLs. Examine (TEM for ferritin or autoradiography + TEM for 125-I) and compare normal vs FH- labeling Expected results: Binding of LDLs is seen in coated pits of normal fibroblasts, but not in cells from FH- individuals....
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- Spring '08
- Coated Pits, normal cells vs, FH- cell fluorescence, FHindividuals