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Cell case studies - Chapter 5 Cell Structure and Function Lecture Activity 3 Handout Cell Structure and Function Case Studies Case 1

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Chapter 5 Cell Structure and Function Lecture Activity 3 Handout – Cell Structure and Function Case Studies Case 1 Erythrocytes (red blood cells) have no nucleus, mitochondria, or other organelles at maturity. These organelles are ejected when the RBC enters the bloodstream, or shortly thereafter. Should this still be considered a cell? What will be the effect of having no nucleus? In these cells, the lack of mitochondria is an advantage. Why? Because the cells have no nucleus, they cannot divide, or replace worn out plasma membrane. The plasma membrane becomes fragile and the cell eventually dies after 80–120 days, usually by rupturing in the spleen. The RBC is still considered to be a eukaryotic cell (although a dying one), because it had a nucleus and other organelles at one time in its life. http://www.rothamsted.bbsrc.ac.uk/notebook/courses/gu ide/blood1.htm Case 2 Pompe’s disease is one of a class of lysosomal storage diseases in which one or more enzymes that are normally found in the lysosomes are defective or absent. In Pompe’s disease, the enzyme that normally breaks down glycogen is absent. Describe what you would see in an electron micrograph of a liver cell from an individual with Pompe’s disease. What are some possible consequences of having such a disease? Can you think of an effective way to treat it? An electron micrograph would show large lysosomes,
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This note was uploaded on 08/23/2011 for the course BIO 1005 at Virginia Tech.

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Cell case studies - Chapter 5 Cell Structure and Function Lecture Activity 3 Handout Cell Structure and Function Case Studies Case 1

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