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Unformatted text preview: HIV/AIDS Page 1 HIV/AIDS Some History 1960s-1970s • Blood Products Industries The Blood Products Industries developed in the late 1960s and began to mix Blood from multiple Donors. This created a small Pool for the direct Blood-to-Blood Transmission of Pathogens, particularly Viruses. • IV Drugs Cheap disposable Syringes came on the Market in the Mid-1960s. Heroin was easily available and widely used in Vietnam. And IV Drug Use was on the Rise in Inner City Areas. Another, much larger Pool for the direct Blood-to-Blood Transmission of Viruses was created. • The Sexual Revolution It began with the Release of The Pill in 1960. Recreational Sex became popular, as did the Practice of having Sex with Multiple Partners, either simultaneously or in succession. An enormous Pool for Sexual Transmission of Pathogens grew. The Spread of Venereal Diseases was increasing to near Epidemic Proportions. • The Gay Revolution The Gay Revolution was simply another Aspect of the Sexual Revolution. Multi-Partner, Versatile Sex at Gay Bath Houses created a small Pool for the Sexual Transmission of Pathogens and Viruses. The Spread of Venereal Diseases was increasing to near Epidemic Proportions. Blood Product Industries, IV Drug Use, The Sexual Revolution and the Gay Revolution together made up rapidly enlarging and increasingly interconnected Pools for the Transmission of Pathogens. Meanwhile, starting in the early 1970s... • Kaposi ʼ s Sarcoma would appear in Kidney Transplant Patients on Immunosuppressive Therapy • Kaposi ʼ s Sarcoma would regress upon Cessation of Treatment Prior to the 1970s Kaposi ʼ s Sarcoma was considered so unusual that whenever a Case appeared in a larger Hospital, all the Residents were called in to have an Opportunity to look at this rare Form of Cancer. Classic Kaposi ʼ s Sarcoma is characterized by the Appearance of purple Nodules, particularly in the Lower Extremities. The Nodules are Proliferations of Spindle Cells (Small Blood Vessels filled with Erythrocytes), Hemorrhages and Deposits of Hemosiderin. Cytomegalovirus seems to be associated with Kaposi ʼ s Sarcoma. So by the End of the 1970s most Physicians associated Kaposi’s Sarcoma with Immunosuppression. HIV/AIDS Page 2 The Late 1970s • “Patient Zero” Gaetan Dugas -- an Air Canada Flight Attendant -- probably picked-up HIV while in Port au Prince, Haiti, the Bangkok of the late 1970s. HIV seems to have evolved from the closely related Simian Immunodeficiency Virus (SIV) in Cameroon in West Africa in the 1930s. A Blood-borne, Sexually and/or Blood-to-Blood Transmitted Virus was inoculated into the Bath House Culture for Amplification. July 1981 • Centers for Disease Control (CDC) received 5 Requests for the experimental Drug Pentamidine - Pentamidine was undergoing Trials as a Drug to treat Pneumocystis carinii Pneumonia (PCP) - There had only been 2 Requests during the previous 12 Years - All 5 new Cases were young gay Men from Los Angeles...
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