153Cwinter09Finalexam

153Cwinter09Finalexam - Final Exam, Chemistry 153C, Winter...

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Final Exam, Chemistry 153C, Winter 09 Please print and sign your full name below and provide your student ID. On the subsequent pages, please print your last name. The exam should be completed in 3 hours. The only materials allowed on your desk are pencil/pen and eraser. Calculators are not needed and books and notes are not allowed. Printed Name _____ Last, First Student ID # Signature __ Points: Page 2 /16 Page 3 /24 Page 4 /24 Page 5 /25 Page 6 /22 Page 7 /16 Page 8 /22 Page 9 /13 Page 10 /23 Page 11 /15 Total /200 Points /400 Extra Credit /10 Grade
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Page 2 of 12 Final Exam, Chem 153C, Winter 09 Name______________________________ 1. Remember to relax and breathe deeply 2. Guest speaker Deepa Dabir discussed neurodegenerative diseases and neurotransmitters. A) Name a protein that when defective has been linked to the following neurodegenerative diseases (4 points) Lou Gehrig’s Disease (ALS)___________________________________ Parkinson’s Disease _________________________________________ Huntington’s Disease_________________________________________ Alzheimer’s Disease_________________________________________ (B) Neurons and glial cells work together by sharing amino acids. Show with a general drawing how a 5-C amino acid is shared by neurons and glial cells and include enzyme names for the key reactions (6 points). (C) For the reactions in the neuron described in B, how is ammonia handled so as not to promote toxicity? Provide 3 likely pathways in which the ammonia is handled and justify your answer. (6 points)
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Page 3 of 12 Final Exam, Chem 153C, Winter 09 Name______________________________ 3. A. The following compounds are terpenoids derived from plant species in tropical regions. These derivatives have been purified and found to have anti-cancer and anti-inflammatory properties. Trace the isoprenoid units. (6 points) Costunolide Pinene Sitosterol (B) Assume the isoprenoid precursor to Sitosterol is similar to that of cholesterol, calculate the following number of energy molecules required to make the precursor compound (the linear isoprenoid that is generated
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This note was uploaded on 08/26/2011 for the course CHEMISTRY Chem 153C taught by Professor Cathyclarke during the Spring '11 term at UCLA.

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153Cwinter09Finalexam - Final Exam, Chemistry 153C, Winter...

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