153A_syllabus_Spring2010

153A_syllabus_Spring2010 - CHEM 153A Biochemistry:...

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CHEM 153A – Biochemistry: Introduction to Structure, Enzymes, and Metabolism Spring 2010 Instructor Rebecca Nelson, Ph.D. email: rebecca@chem.ucla.edu phone: 310-825-1670 office: Young Hall 2304 Teaching assistants Natalie Anderson njanderson2@gmail.com Carly Ferguson carly@chem.ucla.edu Alex Jacobitz jacobitz@chem.ucla.edu Catherine Leettola cleettol@ucla.edu Khiem Tran ktran@chem.ucla.edu Huimin Zhang huiminzhang@ucla.edu Lectures 1) MTWF 10:00-10:50 am, CS 24 2) MTWF 12:00-12:50 pm; MWF in CS 76, T in CS 50 Please attend the lecture in which you are enrolled. Textbook Voet, Voet, and Pratt. Fundamentals of Biochemistry: Life at the Molecular Level, 3rd Edition. Wiley, 2008. The shorter, customized text is sufficient for this course; consider buying the full text if you plan to take 153B/C. Course website http://web.chem.ucla.edu/~rebecca/153A/ Tentative lecture schedule WEEK DATE, DAY TOPIC PAGES IN TEXT QUIZZES & EXAMS* 1 Mar 29 M Introduction & overview 1-19 30 T Water 22-30 31 W Acid-base chemistry, Buffers 30-36 Apr 2 F Functional groups and amino acids 74-89, 453 2 5 M Protein sequence and evolution 91-93, 114-120 Amino acids quiz beginning on Wednesday in discussion this week 6 T Protein structure 125-140 7 W Protein structure 145-151 9 F Protein structure and folding 154-162, 165 3 12 M Methods in protein structure analysis 104-113, 141-145, 151-154 Carbohydrates quiz beginning on Wednesday in discussion this week 13 T Carbohydrates – mono & disaccharides 219-228 14 W Carbohydrates – oligo & polysaccharides 228-242, 544 16 F Lipids 245-259 4 19 M Membranes 260-278 Exam 1, Thu Apr 22, 5:00-6:50 pm 20 T Membranes; Q&A 21 W Molecular binding and allostery 193 23 F Myoglobin & Hemoglobin
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153A_syllabus_Spring2010 - CHEM 153A Biochemistry:...

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