1-423-08Membranes

1-423-08Membranes - Behavior of amphipathic lipids in...

Info iconThis preview shows pages 1–8. Sign up to view the full content.

View Full Document Right Arrow Icon
Behavior of amphipathic lipids in aqueous solution Bilayers NOT very permeable to ions and polar molecules
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Membranes are not simply lipid bilayers… Fluid mosaic model Membranes are asymmetric… Membranes are fluid…what factors important in fluidity? …Length and degree of saturation of fatty acid tails of membrane phospholipids
Background image of page 2
Longer = less fluidity (higher melting temperature) More saturated = less fluidity (higher melting temperature)
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Also, sterol molecules in membranes affect membrane fluidity Temperature of surroundings affect membrane fluidity
Background image of page 4
Positions of membrane proteins Integral membrane proteins are often α -helical through the membrane
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Energetic considerations Transporters (carriers): overview -Show conformational changes -Active, passive -Process called membrane transport or carrier-mediated diffusion
Background image of page 6
Transport is similar to enzymes-substrate reactions: -Binding is stereospecific -Binding occurs through weak, noncovalent interactions, at a binding site analogous to an active site
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 8
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 04/05/2008 for the course BIOCHEM 423 taught by Professor Osgood during the Spring '08 term at New Mexico.

Page1 / 13

1-423-08Membranes - Behavior of amphipathic lipids in...

This preview shows document pages 1 - 8. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online