Grignard Reaction

Grignard Reaction - Andre Hinojosa 12601675 Partner:...

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Andre Hinojosa 12601675 Partner: Chelsea/ Tara 8/31/10 Grignard Reaction In this experiment, we synthesized phenylmagnesium bromide, a Grignard reagent, under anhydrous conditions. We then used this reagent in the synthesis of carboxylic acid. Grignard reagents are compounds with carbon-metal bonds. It involves an alkyl or aryl halide reacting with magnesium metal in an ether solvent. The alkyl or aryl halide reacts with the magnesium to form a carbon free radical as well as a magnesium-halogen radical. These 2 radicals then react to form the Grignard reagent. The process takes place in ether because ether keeps the surface metal clean to prevent a polymer from forming on the metal surface which allows the reaction to run until all the limiting reagent is used. In our experiment, bromobenzene is added to the ether for the formation of phenylmagnesium bromide. The formation of this reagent reverses the polarity of the bonds and thus makes the carbon highly negatively charged and a great nucleophile. For
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Grignard Reaction - Andre Hinojosa 12601675 Partner:...

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