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Engineering Lotion-Presentation

Engineering Lotion-Presentation - Skin Remedies Inc...

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Engineering Lotion by Season Hill Amanda Robben S R kin emedies, I nc.
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Purpose square6 Develop a moisturizing lotion to treat ichthyosis and xerosis square6 Design the manufacturing procedure for the lotion
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Agenda square6 The Skin square6 Skin Disorders square6 Treatment square6 Consumer Satisfaction Model square6 Demand Model square6 Manufacturing Process square6 Economic Analysis square6 Future
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The Skin
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The Skin square6 Functions as a barrier to provide immunity from disease square6 Repairs itself daily by replacing the outer layer square6 Contains three layers: epidermis, dermis and subcutaneous Source: http://cancer.healthcentersonline.com/skincancer/basalcellcarcinoma.cfm
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Epidermis square6 The outermost layer of skin square6 Composed of several layers ring2 Stratum Corneum (1) is outermost layer of the epidermis Source: www.eucerim.co.uk
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Stratum Corneum square6 Interacts directly with environment square6 Approximately 20 cell layers thick square6 Location in which desquamation occurs ring2 Desquamation is the shedding of the top layer of cells in the stratum corneum ring2 Approximately 1 layer per day is released
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Stratum Corneum (cont.) square6 Contains hydrophilic cells surrounded by a hydrophobic lipid bilayer ring2 The lipid bilayer prevents water removal from the skin to the atmosphere square6 Contains natural moisturizing factors (NMF) responsible for the absorption and retention of water ring2 Water content is about 30% www.cerave.com/barrier.htm
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Skin Disorders
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Xerosis (Dry Skin) square6 Reduced water content in Stratum Corneum square6 Occurs when natural moisturizers on the skin’s surface are removed square6 Caused by overexposure to water, sun, or cold weather square6 Symptoms include dry, itchy skin
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Ichthyosis square6 Genetic disorders in the production and/or desquamation of cells ring2 Rapid production of skin cells ring2 Desquamation is slowed or inhibited square6 Results in dry and thickened, scaly skin square6 Incurable disorders Source: Geneva Foundation for Medical Education and Research, www.gfmer.ch
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Ichthyosis Vulgaris square6 Accounts for 95% of all ichthyosis cases square6 Affects 1 in 250 people square6 Caused by low water content in Stratum Corneum ring2 The enzymatic reactions controlling desquamation are inhibited Source: www.ichthyosis.com
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Effects on Skin Barrier square6 Reduced or low water content in the Stratum Corneum results in a compromised barrier square6 This compromised barrier must be restored in order to prevent excessive water loss Compromised Barrier Intact Barrier Source: http://www.cetaphil.com.au/importance_of_your_skin_more.asp
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Treatment
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Current Treatment square6 Temporary and symptomatic square6 Primarily focus on supplying ingredients that replenish and retain water content square6 However, there are three key steps to effectively treat the disorders: 1) Promote desquamation 2) Deliver moisturizing agents to underlying skin 3) Restore the skin’s lipid bilayer
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Moisturizer Formulation square6 The simplest vehicle for
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