Electrical gradient produces a membrane potential

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Unformatted text preview: l gradients • Inside of the cell is negative relative to the outside of the cell. • Electrical gradient produces a membrane potential (voltage) Resting Membrane Potential • At equilibrium, inside of the cell membrane would have a higher [negative charges] than the outside. • Potential difference: • Na is Not allowed in; K is K ontained. – Magnitude of difference in charge on the 2 sides of the membrane.. • Depends upon 2 factors: 2 3 Cell Excitability (= Irritability) • The ability to undergo rapid changes in membrane potential in response to stimuli. – Oocytes: rapid block to polyspermy. – Neurons: conduct nerve impulses – Muscle cells: initiate contraction – Ratio of the concentrations of each ion on the 2 sides of the plasma membrane. – Specific permeability of membrane to each different ion. • Resting membrane potential of most cells ranges from - 65 to – 85 mV. Conduction of electrochemical signals in neurons • Nerves are NOT wires! • Nerve impulses are NOT electricity! • Nerve impulse ar...
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