Metabolism

Metabolism - LR/CC/FNB UNIT 2 :Nutrition Topic 7 :...

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Unformatted text preview: LR/CC/FNB UNIT 2 :Nutrition Topic 7 : Metabolism LR/CC/FNB 1: Distribution & Allocation L Food for all the tissues in the body L Key organ liver L Food distribution needs to respond to L Fluctuations in food intake L Changes in energy demand by tissues L Regulated by 2 key hormones, L Insulin & Glucagon LR/CC/FNB 2: Insulin L 51 amino acid polypeptide L 2 chains of 21 and 30 aa L Produced by β cells in pancreas as proinsulin N Secretes about 40 – 50 units per day L Secretion stimulated by; L Increase in blood glucose L Growth hormones and some drugs L Short circulation half-life, 3-5 mins L Inhibited by adrenaline LR/CC/FNB 3: Glucagon L 21 amino acid single chain polypeptide L Produced in α cells of pancreas L Secretion inhibited by high glucose L Stimulated by low glucose L Opposes insulin action L Stimulates gluconeogenesis & glycogenolysis L Promotes fat and protein breakdown L Is an insulin agonist LR/CC/FNB 4: Insulin Action L Promotes uptake of glucose into cells from the blood. (liver makes glycogen) L Decreases protein breakdown L Decreases fat breakdown L Inhibits glucose synthesis in cells L (gluconeogenesis) LR/CC/FNB 5: Normal fluctuations L Arise from time between meals L Insulin & Glucagon act together to balance blood glucose level L Maintain energy supply by maintaining constant blood glucose level LR/CC/FNB...
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This note was uploaded on 07/04/2011 for the course BIO microbiolo taught by Professor Point during the Spring '09 term at HKU.

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Metabolism - LR/CC/FNB UNIT 2 :Nutrition Topic 7 :...

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